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  • Spironolactone is given by mouth and is used off label to treat congestive heart failure, fluid accumulation, and other cardiovascular problems. Common side effects include increased drinking and urinating, mild decreases in energy, mild electrolyte imbalances, or vomiting/diarrhea. Do not use in pets that are allergic to it, have elevated potassium levels, Addison’s disease, acute kidney failure, significant kidney disease, that are not urinating or that may be used for breeding. If a negative reaction occurs, please call your veterinary office.

  • Spondylosis deformans is a condition that affects the vertebral bones of the spine and is characterized by the presence of bony spurs or osteophytes along the edges of the bones of the spine. Spondylosis deformans is a chronic condition that is associated with aging and most cats show no symptoms. This condition is usually diagnosed from X-rays of the spine. Treatment recommendations depend on the individual cat and whether they are showing any clinical signs, such as pain and difficulty with movement.

  • Squamous cell carcinoma (SCC) is a tumor of the cells that make up the contact or upper layer of the skin. UV light exposure has been described as a developmental factor in people and appears to be associated with its development in cats. Areas affected include the ear tips, skin, toes, or peri-ocular region. Fine needle aspiration or biopsy may be performed for diagnosis. The metastatic rate does not appear overly clear, though staging is always recommended. SCC of the toe can occur as a primary tumor or may have spread from the lung (lung-digit syndrome). Surgery is almost always recommended in any case of SCC; the role of chemotherapy is controversial. Radiation therapy has an excellent response rate in cats with the SCC affecting the nasal planum and may give long-term tumor control.

  • St. John’s wort is given by mouth and is used over the counter to treat pain, depression, anxiety, and other conditions. Give as directed by your veterinarian. The most common side effects include gastrointestinal upset, sun sensitivity, skin reactions, allergic reactions, dry mouth, or restlessness. Do not use in pets that are allergic to it, pregnant, nursing, very young, or very old or debilitated. If a negative reaction occurs, please call your veterinary office.

  • Stanozolol is given by mouth and is used off label to treat poor appetite, anemia, tracheal collapse, and other conditions. Give as directed by your veterinarian. Side effects may include behavior changes, limb swelling, or prevention of heat cycles. Do not use in pets that are allergic to it, are pregnant, breeding, or nursing. Pregnant women should NOT handle this medication. If a negative reaction occurs, please call your veterinary office.

  • Stem cells are unspecialized cells that are capable of renewing themselves though cell division. Under certain conditions, they can become a specific tissue or organ cell. Stem cell therapy commonly refers to the process of placing stem cells from the body into diseased or damaged tissues, such as a torn ligament in the knee or perhaps an arthritic joint. This process is often referred to as regenerative medicine. Adult stem cells are capable of repair and regeneration of various tissues because they have the potential to differentiate into specialized cells of an organ. The most common use of stem cell therapies has been in the treatment of osteoarthritis in dogs and cats. Currently, there are no current guidelines with respect to stem cell therapy. Stem therapy should only be performed by a veterinarian with special training, who understands the benefits and limits of this therapy. It is important to have realistic expectations as positive outcomes cannot be guaranteed.

  • This handout discusses the use of corticosteroid (such as prednisone or dexamethasone) in the cat. Reasons for their use as well as the common short-term and long-term side effects of these drugs are outlined, along with strategies to avoid these effects.

  • Stomach tumors are uncommon in dogs and cats. There are many kinds, including leiomyosarcomas, lymphomas, adenocarcinomas, mast cell tumors, fibrosarcomas, plasmacytomas, gastrointestinal stromal tumors (GISTs), and carcinoids (all malignant); and leiomyomas, adenomatous polyps, and adenomas (benign). Most tumors are malignant. Stomach tumors are more prevalent in older animals, males, and certain breeds. The signs of stomach tumors include chronic vomiting, inappetence, lethargy, and weight loss. Sometimes tumor ulceration will cause anemia. Paraneoplastic syndromes are possible with the muscle tumors. Stomach tumors may be diagnosed with imaging, endoscopy, or surgery, with a biopsy. Treatment may involve surgery, chemotherapy, or radiation therapy.

  • Strokes are rare in cats. Some causes include a blood clot such as a thrombus or embolus that lodges in a cerebral blood vessel, cerebral bleeding from trauma, or a blood clotting disorder; however, the cause is often unknown. Signs of a stroke are variable depending on the regions of the brain affected and the degree and duration of blood and oxygen deprivation. Magnetic resonance imaging is the ideal diagnostic test for diagnosing a stroke. Treatment is complex and there is no guarantee of complete success. Your veterinarian will help you assess progress and plan remedial action.

  • Struvite bladder stones are one of the most common bladder stones in cats. In some cats, struvite bladder stones form because of a urinary tract infection. Signs of bladder stones typically include frequent urination, straining to urinate, blood in the urine, and urinating outside of the litterbox. If your cat is having urinary issues, your veterinarian will first recommend a urinalysis. Blood tests, abdominal X-rays, and ultrasound may also be recommended. Medical dissolution and surgical removal are two categories of treatment. Cats who have developed struvite bladder stones are likely to experience a recurrence later in life, unless the conditions that led to the formation of stones can be corrected.